Researchers found that it significantly reduced immobility times within a forced swim test and tail suspension test. In fact, the effect of licorice was similar to that of two common antidepressants, fluoxetine (Prozac) and imipramine (Trofinal).

After further investigation, researchers found that licorice appeared to increase levels of norepinephrine and dopamine, but not serotonin. Based on the antidepressant effects observed, the researchers concluded that licorice extract may, in fact, offer an alternative remedy for depression........

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